Data augmentation strategies based on individualized eating behavior models in patients with type 1 diabetes

Thesis Proposal Details

Supervisor: Giacomo Cappon

Co-supervisor: Francesco Prendin

Co-supervisor Department/Company: DEI

Creation Date: 24/06/2025 10:11

Description

This thesis aims to develop individualized data augmentation strategies for type 1 diabetes based on personal eating patterns. It begins with an analysis of a real-world dataset to characterize meal distributions (breakfast, lunch, dinner, snacks) across pediatric age groups.

A MATLAB interface is developed to define hyperparameters for Gaussian Mixture Models (GMMs), which model each subject’s meal timing. The resulting GMMs are linked to specific meals, forming a personalized library.

Each test subject is matched to the most similar training subject based on their GMM. Meal generators are then built using the matched subject’s model to produce realistic, individualized meal patterns.

These synthetic meals are used to simulate glucose traces, from which glycemic metrics—such as time in, below, and above range—are extracted. The goal is to assess whether increasing synthetic data leads to convergence of glycemic outcomes, supporting more robust, personalized modeling for diabetes management.

Dataset and methods

Dataset type: Already acquired data

Dataset description: Il dataset utilizzato per il presente lavoro di tesi è ‘Tidepool dataset’, ossia una raccolta di dati generati da 300 pazienti con diabete di tipo 1 sottoposti a diverse terapie insuliniche.

List of Methods: Gaussian Mixture Model, Wasserstein Type Distance in the space of Gaussian Mixture Model, Dissimilarity matrix e Multidimensional scaling

Tags
dataaugmentation digitaltwin gmm matlab python tidepool type1diabetes
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